MENURUNNYA KADAR HEMOGLOBIN PADA PENDERITA END STAGE RENAL DISEASE (ESRD) YANG MENJALANI HEMODIALISIS DI KOTA MALANG

Abstract

Incidence of kidney failure in Indonesia has increased by 20% annually, an estimated 70,000 people in 2011, 4,000-5,000 people are detected with end-stages renal failure and undergoing hemodialysis. The hemodialysis process causes some blood trapped or left in the hemodialysis device, some red blood cells are damaged and folic acid decreases. The aims of this study was to know the difference of hemoglobin (Hb) profile in End Stages Renal Disease (ESRD) patients based on duration of hemodialysis at RS “S” Malang. The research method used a comparative design with a sample of 100 respondents. Anova test showed the difference of Hb level profile in ESRD patients based on duration of hemodialysis from 1 year up to 10 years (p = 0,03; α = 0,05), which means that the longer the hemodialysis then the Hb level decreases. Anemia is a complication of ESRD, the decrease in Hb resulting from disruption of the production of the hormone erythropoietin, in addition, hemodialysis process also exacerbates the degree of anemia where some red blood cells trapped in hemodialysis, red blood cells are damaged, and folic acid decreased due to dissolved in fluid dialysis. Furthermore, it is necessary to examine related factors that cause the decrease in Hb in patients with ESRD with hemodialysis therapy both intrinsic and extrinsic factors.

Keywords: hemoglobin, ESRD, hemodialysis